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CS-W001157 4
Total: USD 88.00

4-Bromo-2-isopropylphenylboronic acid

  • CAS No. 1451390-88-7

  • Cat. No. CS-0189757
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-isopropylphenylboronic acid|CS-0189757

Structure of 1451390-88-7

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General Information

  • CAS No. 1451390-88-7
  • Cat. No. CS-0189757
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂BBrO₂
  • Molecular Weight 242.91
  • Synonym(s) (4-Bromo-2-isopropylphenyl)boronic acid
  • SMILES CC(C)C1=C(C=CC(=C1)Br)B(O)O

Description

4-Bromo-2-isopropylphenylboronic acid features a boronic acid group flanked by bromine and isopropyl substituents on a phenyl ring, enabling selective cross-coupling in Suzuki-Miyaura reactions. The sterically hindered isopropyl group enhances stability, while the bromine facilitates downstream functionalization. This arylboronic acid delivers predictable reactivity under standard conditions, streamlining access to complex biaryl architectures.

Application

4-Bromo-2-isopropylphenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its stability under ambient conditions and compatibility with diverse reaction partners facilitate reliable C–C bond formation. The isopropyl group provides steric bulk that can influence regioselectivity in subsequent transformations, while the bromo substituent offers orthogonal reactivity for sequential functionalization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.2523
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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