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Structure of 1451391-42-6
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This boronate moiety integrates a cyano and methyl group at the meta- and para-positions relative to the boronic acid, enhancing electronic and steric control. The electron-withdrawing cyano group stabilizes the boronate under standard conditions, while the methyl substituent improves solubility and reactivity in Suzuki-Miyaura couplings.
(3-Cyano-5-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its cyano and methyl groups confer enhanced electronic stability and ortho-directed functionalization potential, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction partners. Ideal for medicinal chemistry campaigns requiring precise substitution patterns and scalable synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: