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Structure of 1451391-51-7
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This boronate moiety features a sterically hindered aryl core with electron-withdrawing chlorine substituents and a methyl group at the 4-position, enhancing stability and tuning reactivity. Designed for efficient Suzuki-Miyaura coupling, it delivers reliable cross-coupling under standard conditions with minimal protodeboronation.
(2,6-Dichloro-4-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-chlorine substituents enhance stability and facilitate downstream functionalization, while the methyl group provides steric and electronic tuning. The compound exhibits excellent bench stability, ease of purification, and broad functional group tolerance, making it well-suited for the synthesis of complex arylated scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: