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Structure of 1454558-46-3
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This boronate moiety integrates seamlessly into Suzuki-Miyaura couplings, offering enhanced stability and solubility under standard conditions. The 1-methyl-2-oxo-1,2-dihydropyridin-3-yl scaffold provides a rigid, electron-deficient platform ideal for coupling with aryl halides, enabling efficient access to functionalized heterocycles in medicinal chemistry and materials synthesis.
(1-Methyl-2-oxo-1,2-dihydropyridin-3-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of functionalized pyridine derivatives. Its boronic acid moiety facilitates Suzuki-Miyaura coupling with high chemoselectivity and stability under ambient conditions. The 1-methyl-2-oxo substituent enhances solubility and reduces protodeboronation, offering improved bench stability and ease of purification. This reagent functions effectively in the synthesis of biologically relevant heterocyclic scaffolds and advanced intermediates for medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: