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Structure of 145783-14-8
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4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine features a trifunctional pyrimidine core with electron-withdrawing chlorine and nitro groups paired with a propylthio substituent. This combination enables selective reactivity in nucleophilic substitution cascades, facilitating efficient incorporation into advanced heterocyclic architectures under mild conditions.
4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine serves as a versatile building block in heterocyclic synthesis, enabling selective functionalization at the 4- and 6-positions via palladium-catalyzed cross-coupling. The nitro group facilitates subsequent reduction and cyclization sequences, while the propylthio substituent offers orthogonal reactivity. Its bench-stable nature and compatibility with diverse nucleophiles make it valuable for constructing complex pyrimidine-based scaffolds in medicinal chemistry and agrochemical development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: