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Structure of 1458576-00-5
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Biotin-PEG4-alkyne features a short, hydrophilic PEG4 spacer flanking a terminal alkyne group, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation. The biotin moiety provides high-affinity binding to streptavidin and avidin, while the PEG4 linker enhances solubility and reduces non-specific interactions. This bifunctional reagent streamlines site-specific labeling in protein and nucleic acid conjugations under standard conditions.
Biotin-PEG4-alkyne serves as a versatile bifunctional linker for bioconjugation, enabling site-specific labeling via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The PEG4 spacer provides enhanced solubility and reduced steric hindrance, while the alkyne group offers high reactivity with azides under mild conditions. This reagent facilitates efficient immobilization or detection of biomolecules in pull-down assays, affinity purification, and fluorescent labeling workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: