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Structure of 14618-45-2
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3-(Trifluoroacetyl)indole features a strongly electron-withdrawing trifluoroacetyl group attached to the indole scaffold, enhancing electrophilicity at the 3-position. This substitution enables direct functionalization in cross-coupling and cyclization reactions, serving as a key intermediate in the synthesis of complex heterocycles and bioactive molecules under mild conditions.
3-(Trifluoroacetyl)indole serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the indole C3 position. The trifluoroacetyl group provides enhanced electrophilicity for nucleophilic substitution and facilitates subsequent deprotection or transformation into diverse indole derivatives. Its bench stability and compatibility with standard reaction conditions make it well-suited for medicinal chemistry campaigns and heterocycle synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: