4-Amino-3-hydroxybenzamide

Name: 4-Amino-3-hydroxybenzamide
Brand: ChemScene
Availability: InStock
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CAS No. 146224-62-6
Cat. No. CS-0149976
Purity≥95%
MDL No.MFCD16999380

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 146224-62-6

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Description

4-Amino-3-hydroxybenzamide features a strategically positioned amino group and phenolic hydroxyl, enabling dual hydrogen-bonding interactions. This scaffold integrates readily into bioactive molecule design, offering enhanced solubility and structural rigidity for medicinal chemistry applications under standard conditions.

Application

4-Amino-3-hydroxybenzamide serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds and bioactive molecules. Its ortho-dihydroxy-amino substitution pattern facilitates metal-catalyzed coupling reactions and cyclization processes under mild conditions. The compound exhibits good bench stability and is readily purified by recrystallization or flash chromatography, supporting its use in multi-step synthetic sequences for API development.

General Information

CAS No. 146224-62-6
Cat. No. CS-0149976
Purity ≥95%
MDL No. MFCD16999380
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₂O₂
Molecular Weight 152.15
Synonym(s) Benzamide, 4-amino-3-hydroxy- (9CI)
SMILES NC(C1=CC(O)=C(N)C=C1)=O

Computational Chemistry Data

TPSA 89.34
LogP 0.0733
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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4-Amino-3-hydroxybenzamide

CAS No. 146224-62-6

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