Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(tert-Butyl) 3-ethyl 2,5-dihydro-1H-pyrrole-1,3-dicarboxylate

  • CAS No. 146257-00-3

  • Cat. No. CS-0079118
  • Purity≥98%
  • MDL No.MFCD11973978

*For research and further manufacturing use only, not for direct human use.

1-(tert-Butyl) 3-ethyl 2,5-dihydro-1H-pyrrole-1,3-dicarboxylate|CS-0079118

Structure of 146257-00-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 146257-00-3
  • Cat. No. CS-0079118
  • Purity ≥98%
  • MDL No. MFCD11973978
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉NO₄
  • Molecular Weight 241.28
  • Synonym(s) Ethyl N-Boc-2,5-dihydropyrrole-3-carboxylate
  • SMILES O=C(N1CC(C(OCC)=O)=CC1)OC(C)(C)C

Description

This 1-(tert-butyl) 3-ethyl 2,5-dihydro-1H-pyrrole-1,3-dicarboxylate features a sterically hindered tert-butyl group and an ethyl ester moiety that together enhance solubility and stability. The dihydropyrrole core provides a reactive scaffold for transition-metal-catalyzed transformations. Bench-stable under standard conditions, it serves as a key building block in the synthesis of complex heterocycles and bioactive molecules.

Application

1-(tert-Butyl) 3-ethyl 2,5-dihydro-1H-pyrrole-1,3-dicarboxylate serves as a versatile dihydropyrrole building block for heterocyclic synthesis. Its sterically shielded tert-butyl and ethyl ester groups enable enhanced bench stability and compatibility with diverse functional groups. The molecule facilitates efficient cyclization and conjugate addition reactions, supporting the construction of complex nitrogen-containing scaffolds in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Wang, Xifang; Espinosa, Juan F.; Gellman, Samuel H. Journal of the American Chemical Society, 2000 , vol. 122, # 19 p. 4821 - 4822
  • Route2

    References

    • Wang, Xifang; Espinosa, Juan F.; Gellman, Samuel H. Journal of the American Chemical Society, 2000 , vol. 122, # 19 p. 4821 - 4822

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   55.84
  • LogP   1.7266
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 146257-00-3 sigma146257-00-3 manufacturer146257-00-3 price146257-00-3 structure146257-00-3 SDSbuy 146257-00-3146257-00-3 supplier146257-00-3 uses146257-00-3 molecular weightprice of 146257-00-3146257-00-3 chemical name formula of 146257-00-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label