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CS-W001157 4
Total: USD 88.00

N4-Acetylcytosine

  • CAS No. 14631-20-0

  • Cat. No. CS-W010939
  • Purity≥96%
  • MDL No.MFCD00134466

*For research and further manufacturing use only, not for direct human use.

N4-Acetylcytosine|CS-W010939

Structure of 14631-20-0

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General Information

  • CAS No. 14631-20-0
  • Cat. No. CS-W010939
  • Purity ≥96%
  • MDL No. MFCD00134466
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N₃O₂
  • Molecular Weight 153.14
  • Synonym(s) 4-N-Acetylcytosine
  • SMILES O=C1N=CC=C(NC(C)=O)N1

Description

Four stable conformers of N4-acetylcytosine, and the one of the stable form containing an intramoleuclar six-membered ring have been reported by theoretical calculations.The infrared and FT-Raman spectra of N4-acetylcytosine in the solid phase has been reported.N4-Acetylcytosine may be used in the preparation of cytidine. It may be used in the preparation of 1-(4-azido-4-deoxy--D-glucopyranosyl)cytosine.

Synthesis

  • Route1
    • Cytosine Lamivudine Impurity|CS-0214072
      71-30-7
    • null|null
      108-24-7
    • ~94%
    • In-stock
      N4-Acetylcytosine|CS-W010939
      14631-20-0

    References

    • Okabe; Sun; Zenchoff Journal of Organic Chemistry, 1991 , vol. 56, # 14 p. 4392 - 4397
  • Route2
    • 4-Amino-1-((1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidin-2(1H)-one|CS-0859712
      32830-01-6
    • ~19%
    • In-stock
      N4-Acetylcytosine|CS-W010939
      14631-20-0
    • null|null
      84856-79-1
    • null|null
      58538-06-0

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 47, # 11 p. 2961 - 2968
  • Route3
    • N-(1-((2R,4S,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide|CS-0868185
      40094-20-0
    • ~%
    • In-stock
      N4-Acetylcytosine|CS-W010939
      14631-20-0
    • null|null
      65475-52-7

    References

    • Tetrahedron, , vol. 40, # 1 p. 125 - 135

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.85
  • LogP   -0.2717
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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