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Structure of 14631-46-0
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5,6,7,8-Tetrahydroquinolin-8-ol features a saturated quinoline core with a strategically positioned hydroxyl group at the C8 position, enabling direct functionalization in synthetic routes. This bench-stable scaffold integrates readily into bioactive molecule frameworks, offering enhanced solubility and metabolic stability compared to fully aromatic analogs.
5,6,7,8-Tetrahydroquinolin-8-ol serves as a versatile scaffold in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its phenolic hydroxyl group offers direct functionalization potential, while the saturated ring system enhances metabolic stability and solubility. The compound exhibits robust bench stability and facilitates straightforward derivatization via coupling reactions or electrophilic substitution, making it a practical building block for lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: