Fmoc-Ala-OMe

Name: Fmoc-Ala-OMe
Brand: ChemScene
Availability: InStock
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CAS No. 146346-88-5
Cat. No. CS-0041006
Purity≥97%
MDL No.MFCD20264827

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 146346-88-5
Cat. No. CS-0041006
Purity ≥97%
MDL No. MFCD20264827
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₉H₁₉NO₄
Molecular Weight None
Synonym(s) Nα-Fmoc-Ala-OMe
SMILES C[C@@H](C(OC)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

Fmoc-Ala-OMe is a protected alanine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group at the N-terminus and methyl ester functionality at the C-terminus. This combination enables efficient incorporation into solid-phase peptide synthesis workflows, offering stability during coupling steps and ease of deprotection under mild basic conditions. The molecule’s bench-stable nature supports reliable handling in routine laboratory settings.

Application

Fmoc-Ala-OMe serves as a robust building block for peptide synthesis, enabling efficient N-terminal protection and orthogonal deprotection in solid-phase and solution-phase workflows. The fluorenylmethoxycarbonyl (Fmoc) group ensures stable protection under basic conditions, while the methyl ester facilitates straightforward conversion to carboxylic acid derivatives. Its bench-stable nature and compatibility with standard coupling reagents make it ideal for iterative peptide assembly and fragment condensation.

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

TPSA 64.63
LogP 3.0866
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 4

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-Ala-OMe

CAS No. 146346-88-5

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