CY3-SE

Name: CY3-SE
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 146368-16-3
Cat. No. CS-5032
Purity≥95%
MDL No.MFCD29472576

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 146368-16-3

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Description

CY3-SE is a reactive, fluorescent dye featuring a maleimide group for selective conjugation to thiol-containing biomolecules. This derivative delivers bright, photostable labeling under standard conditions, enabling efficient bioconjugation in protein and peptide modification workflows.

Application

CY3-SE is a reactive, maleimide-functionalized cyanine dye that serves as a robust labeling reagent for thiol-containing biomolecules. It enables site-specific conjugation under mild aqueous conditions, offering high stability and low background in bioconjugation workflows. The succinimidyl ester group facilitates efficient coupling with primary amines, while the thiol-reactive maleimide provides orthogonal functionality for dual-labeling strategies. Widely used in protein labeling, immunoassays, and live-cell imaging, CY3-SE combines excellent photostability, strong fluorescence, and ease of purification—making it ideal for routine bench applications requiring reliable, reproducible labeling.

General Information

CAS No. 146368-16-3
Cat. No. CS-5032
Purity ≥95%
MDL No. MFCD29472576
Storage -20°C, sealed storage, away from moisture and light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₅H₄₁N₃O₁₀S₂
Molecular Weight 727.84
Synonym(s) Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
SMILES CC(/C(N1CCCCCC(ON2C(CCC2=O)=O)=O)=C\C=C\C3=[N+](CC)C(C=CC(S(=O)([O-])=O)=C4)=C4C3(C)C)(C)C5=C1C=CC(S(=O)(O)=O)=C5

Computational Chemistry Data

TPSA 181.5
LogP 4.639
H_Acceptors 10
H_Donors 1
Rotatable_Bonds 12

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Life Science Linker Other Linker

Chemical Biology PEGylation PEG Oligomers

Key Words

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CY3-SE

CAS No. 146368-16-3

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