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Structure of 14659-58-6
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2-Bromo-5-fluoro-1,3-dimethylbenzene features a uniquely substituted aromatic core with bromo and fluoro groups positioned meta to each other, flanked by methyl substituents at the 1 and 3 positions. This electronic and steric profile enables selective coupling reactions in pharmaceutical synthesis, particularly in palladium-catalyzed cross-coupling processes where controlled reactivity is essential.
2-Bromo-5-fluoro-1,3-dimethylbenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromine center facilitates efficient Suzuki, Stille, or Negishi coupling, while the fluorine and methyl groups provide electronic modulation and steric control. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses requiring selective functionalization.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: