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CS-W001157 4
Total: USD 88.00

2,6-Dimethoxybenzoic acid

  • CAS No. 1466-76-8

  • Cat. No. CS-0000047
  • Molecule weight182.17
  • Purity≥98%
  • MDL No.MFCD00002437

*For research and further manufacturing use only, not for direct human use.

2,6-Dimethoxybenzoic acid|CS-0000047

Structure of 1466-76-8

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General Information

  • CAS No. 1466-76-8
  • Cat. No. CS-0000047
  • Purity ≥98%
  • MDL No. MFCD00002437
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₄
  • Molecular Weight 182.17
  • Synonym(s) None
  • SMILES O=C(O)C(C(OC)=CC=C1)=C1OC

Description

L-Homophenylalanine is used as a precursor in the pharmaceutical industry for the production of angiotensin-converting enzyme (ACE) and R-(-)-Homophenylalanin-ethylester. It is also involved in the synthesis of NEPA [(S,S)-N-(1-Ethoxycarbonyl-3-phenylpropyl)alanine], which is a key intermediate to prepare the ACE-inhibitors: enalapril, delapril, quinapril and ramipril. It acts as an anti-tumor reagent.

Synthesis

  • Route1
    • null|null
      124-38-9
    • In-stock
      1,3-Dimethoxybenzene|CS-W018510
      151-10-0
    • ~69%
    • In-stock
      2,6-Dimethoxybenzoic acid|CS-0000047
      1466-76-8

    References

    • US6384273 B1, ; Page column 7-8 ;
  • Route2

    References

    • Angewandte Chemie - International Edition, , vol. 41, # 2 p. 340 - 343
  • Route3
    • null|null
      139287-39-1
    • ~75%
    • In-stock
      2,6-Dimethoxybenzoic acid|CS-0000047
      1466-76-8

    References

    • Synthetic Communications, , vol. 22, # 1 p. 13 - 22

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.402
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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