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Structure of 14719-37-0
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Ethyl (tert-butoxycarbonyl)glycinate features a protected glycine scaffold with orthogonal functionality. The tert-butoxycarbonyl group enables selective deprotection under mild acidic conditions, while the ethyl ester supports downstream transformations. This bifunctional design facilitates efficient peptide coupling and sequence assembly in synthetic workflows.
Ethyl (tert-butoxycarbonyl)glycinate serves as a versatile amino acid equivalent in peptide synthesis, enabling controlled Nα-protection and subsequent deprotection under mild acidic conditions. The tert-butyl carbamate group provides excellent stability during standard reaction conditions, while the ethyl ester facilitates efficient hydrolysis or coupling transformations. This compound functions reliably in multi-step sequences requiring orthogonal protection, offering predictable reactivity and ease of purification for bench-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: