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CS-W001157 4
Total: USD 88.00

Ethyl (tert-Butoxycarbonyl)glycinate

  • CAS No. 14719-37-0

  • Cat. No. CS-D0931
  • Purity≥98%
  • MDL No.MFCD05663720
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Ethyl (tert-Butoxycarbonyl)glycinate|CS-D0931

Structure of 14719-37-0

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Description

Ethyl (tert-butoxycarbonyl)glycinate features a protected glycine scaffold with orthogonal functionality. The tert-butoxycarbonyl group enables selective deprotection under mild acidic conditions, while the ethyl ester supports downstream transformations. This bifunctional design facilitates efficient peptide coupling and sequence assembly in synthetic workflows.

Application

Ethyl (tert-butoxycarbonyl)glycinate serves as a versatile amino acid equivalent in peptide synthesis, enabling controlled Nα-protection and subsequent deprotection under mild acidic conditions. The tert-butyl carbamate group provides excellent stability during standard reaction conditions, while the ethyl ester facilitates efficient hydrolysis or coupling transformations. This compound functions reliably in multi-step sequences requiring orthogonal protection, offering predictable reactivity and ease of purification for bench-scale applications.

General Information

  • CAS No. 14719-37-0
  • Cat. No. CS-D0931
  • Purity ≥98%
  • MDL No. MFCD05663720
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₄
  • Molecular Weight 203.24
  • Synonym(s) None
  • SMILES CCOC(CNC(OC(C)(C)C)=O)=O

Computational Chemistry Data

  • TPSA   64.63
  • LogP   1.0742
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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