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Structure of 1473423-59-4
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2,6-Dichloro-4-fluorobenzonitrile features a trifunctional aromatic core with orthogonal reactivity, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient ring supports efficient nucleophilic substitution, while the nitrile group serves as a handle for downstream functionalization. Bench-stable and moisture-tolerant, this building block streamlines synthesis in medicinal chemistry and agrochemical development.
2,6-Dichloro-4-fluorobenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of substituted heterocycles via nucleophilic aromatic substitution. Its orthogonal reactivity profile—driven by the electron-withdrawing nitrile and halogen substituents—facilitates selective functionalization under mild conditions. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring high regiocontrol and compatibility with diverse reaction partners.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: