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CS-W001157 4
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6,6'-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2'-bipyridine

  • CAS No. 147409-41-4

  • Cat. No. CS-0087134
  • Molecule weight378.47
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6,6'-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2'-bipyridine|CS-0087134

Structure of 147409-41-4

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General Information

  • CAS No. 147409-41-4
  • Cat. No. CS-0087134
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₆N₄O₂
  • Molecular Weight 378.47
  • Synonym(s) 6,6 inverted exclamation marka-Bis(4-(S)-isopropyl-2-oxazolinyl)-2,2 inverted exclamation marka-bipyridine
  • SMILES CC(C)[C@H]1COC(C2=NC(C3=NC(C4=N[C@@H](C(C)C)CO4)=CC=C3)=CC=C2)=N1

Application

(S,S)-BiPybox-ipr serves as a robust chiral ligand in asymmetric transition-metal catalysis, enabling high enantioselectivity in reactions such as conjugate additions and C–H functionalizations. Its rigid bispyridyl backbone and sterically defined chiral pocket enhance catalyst stability and reproducibility, while the isopropyl-substituted aryl groups improve solubility and facilitate purification. This ligand functions effectively with palladium, copper, and nickel complexes, offering broad utility in the synthesis of enantiomerically enriched building blocks for pharmaceutical and agrochemical applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   68.96
  • LogP   3.7464
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   5

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