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CS-W001157 4
Total: USD 88.00

2,5-Dibromobenzene-1,4-diol

  • CAS No. 14753-51-6

  • Cat. No. CS-W008047
  • Purity≥97%
  • MDL No.MFCD00192664

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromobenzene-1,4-diol|CS-W008047

Structure of 14753-51-6

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General Information

  • CAS No. 14753-51-6
  • Cat. No. CS-W008047
  • Purity ≥97%
  • MDL No. MFCD00192664
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄Br₂O₂
  • Molecular Weight 267.90
  • Synonym(s) 2,5-Dibromohydroquinone; 2,5-Dibromobenzene-1,4-diol
  • SMILES OC1=CC(Br)=C(O)C=C1Br

Description

Boc-beta-Ala-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Synthesis

  • Route1
    • null|null
      123-31-9
    • ~83%
    • In-stock
      2,5-Dibromobenzene-1,4-diol|CS-W008047
      14753-51-6

    References

    • Journal of Chemical Research - Part S, , # 6 p. 272 - 275
  • Route2

    References

    • Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, , vol. 365, p. 481 - 489
  • Route3
    • 1,4-Dimethoxybenzene, 99%|CS-1269050
      150-78-7
    • ~%
    • In-stock
      2,5-Dibromobenzene-1,4-diol|CS-W008047
      14753-51-6

    References

    • Macromolecules, , vol. 35, # 13 p. 4975 - 4982

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   2.6228
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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