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CS-W001157 4
Total: USD 88.00

(S,S)-iPr-BI-DIME

  • CAS No. 1477517-21-7

  • Cat. No. CS-0034989
  • Purity≥97%
  • MDL No.MFCD31630765
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S,S)-iPr-BI-DIME|CS-0034989

Structure of 1477517-21-7

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Description

(S,S)-iPr-BI-DIME is a sterically hindered, bench-stable chiral ligand featuring two bidentate imine units that enable precise control in asymmetric transition-metal catalysis. This configuration delivers high enantioselectivity in key bond-forming reactions, particularly in nickel- and palladium-catalyzed cross-couplings. The isopropyl substituents enhance solubility and reduce catalyst deactivation pathways.

Application

(S,S)-iPr-BI-DIME serves as a highly effective chiral ligand in asymmetric transition metal catalysis, enabling enantioselective transformations such as hydrogenation and cross-coupling reactions. Its sterically demanding isopropyl groups enhance enantiocontrol and improve catalyst stability, while the rigid biaryl backbone ensures consistent performance across diverse substrates. The ligand exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthetic applications in medicinal chemistry and process development.

General Information

  • CAS No. 1477517-21-7
  • Cat. No. CS-0034989
  • Purity ≥97%
  • MDL No. MFCD31630765
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₉O₃P
  • Molecular Weight 372.44
  • Synonym(s) (2S,3S)-iPr-BIDIME
  • SMILES COC(C=CC=C1OC)=C1C2=C([P@](C(C)(C)C)[C@@H](C(C)C)O3)C3=CC=C2

Computational Chemistry Data

  • TPSA   27.69
  • LogP   5.651
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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