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CS-W001157 4
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Ethyl 2,5-dichloronicotinate

  • CAS No. 148065-10-5

  • Cat. No. CS-0312622
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2,5-dichloronicotinate|CS-0312622

Structure of 148065-10-5

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General Information

  • CAS No. 148065-10-5
  • Cat. No. CS-0312622
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇Cl₂NO₂
  • Molecular Weight 220.05
  • Synonym(s) ethyl 2,5-dichloropyridine-3-carboxylate
  • SMILES CCOC(=O)C1=C(Cl)N=CC(=C1)Cl

Synthesis

  • Route1

    References

    • PFIZER PRODUCTS INC. Patent: WO2005/102389 A2, 2005 ; Location in patent: Page/Page column 207-208 ; WO 2005/102389 A2
  • Route2
    • null|null
      13103-07-6
    • null|null
      107-02-8
    • ~36%
    • Ethyl 2,5-dichloronicotinate|CS-0312622
      148065-10-5

    References

    • Svekhgeimer, M.-G. A.; Kobrakov, K. I.; Pavlov, A. G.; Sychev, S. S. Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 7.1 p. 1048 - 1051 Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 7 p. 1334 - 1338
  • Route3

    References

    • Pfizer Products Inc. Patent: EP1229034 A1, 2002 ; Location in patent: Page 138 ; EP 1229034 B1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   2.5651
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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