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CS-W001157 4
Total: USD 88.00

5,8-Dibromoquinoxaline

  • CAS No. 148231-12-3

  • Cat. No. CS-W005900
  • Purity≥95%
  • MDL No.MFCD18448005
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5,8-Dibromoquinoxaline|CS-W005900

Structure of 148231-12-3

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Description

5,8-Dibromoquinoxaline delivers a sterically constrained, electron-deficient heteroaromatic scaffold ideal for cross-coupling applications. The dibromo substitution pattern enables sequential functionalization, while the quinoxaline core provides robust thermal stability and enhanced solubility in polar aprotic solvents. This compound serves as a key intermediate in the synthesis of advanced materials and bioactive heterocycles.

Application

5,8-Dibromoquinoxaline serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its brominated positions enable palladium-catalyzed cross-coupling reactions with broad functional group tolerance, facilitating efficient access to biaryl and extended π-conjugated systems. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthetic workflows in medicinal chemistry and materials science applications.

General Information

  • CAS No. 148231-12-3
  • Cat. No. CS-W005900
  • Purity ≥95%
  • MDL No. MFCD18448005
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄Br₂N₂
  • Molecular Weight 287.94
  • Synonym(s) 5,8-dibromo-Quinoxaline
  • SMILES BrC1=CC=C(Br)C2=C1N=CC=N2

Computational Chemistry Data

  • TPSA   25.78
  • LogP   3.1548
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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