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CS-W001157 4
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(1S,2S)-1,2-Bis(2-methoxyphenyl)ethane-1,2-diamine

  • CAS No. 148240-65-7

  • Cat. No. CS-0133278
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(1S,2S)-1,2-Bis(2-methoxyphenyl)ethane-1,2-diamine|CS-0133278

Structure of 148240-65-7

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Description

This chiral diamine features two 2-methoxyphenyl groups positioned on adjacent carbons, delivering enhanced solubility and stability in polar solvents. The (1S,2S) stereochemistry ensures high enantioselectivity in asymmetric catalysis, enabling efficient synthesis of chiral intermediates. Its robust framework withstands standard reaction conditions while maintaining structural integrity.

Application

(1S,2S)-1,2-Bis(2-methoxyphenyl)ethane-1,2-diamine serves as a chiral bis(aryl)amine scaffold with defined stereochemistry, enabling the formation of well-defined coordination complexes in asymmetric catalysis. Its ortho-methoxy groups enhance solubility and modulate electronic properties, while the diamine backbone provides robust ligand functionality for transition metal catalysts. The compound exhibits excellent bench stability and facilitates efficient metal complexation under standard conditions, making it a practical choice for enantioselective synthesis workflows.

General Information

  • CAS No. 148240-65-7
  • Cat. No. CS-0133278
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₀N₂O₂
  • Molecular Weight 272.34
  • Synonym(s) (S,S)-1,2-BIS(2-METHOXYPHENYL)-1,2-ETHANEDIAMINE
  • SMILES N[C@@H](C1=CC=CC=C1OC)[C@@H](N)C2=C(OC)C=CC=C2

Computational Chemistry Data

  • TPSA   70.5
  • LogP   2.4036
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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