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Structure of 148258-27-9
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6-(Chloromethyl)nicotinic acid features a reactive chloromethyl group positioned ortho to the carboxylic acid on a pyridine ring, enabling direct functionalization in synthetic transformations. This bifunctional architecture supports efficient conjugation strategies in medicinal chemistry and materials synthesis, where site-specific derivatization is required. The compound exhibits good stability under standard bench conditions and facilitates modular assembly of bioactive scaffolds.
6-(Chloromethyl)nicotinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The chloromethyl group enables efficient nucleophilic substitution, while the carboxylic acid facilitates amide coupling or esterification, offering orthogonal functionalization in complex molecule assembly. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: