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Structure of 1483-55-2
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2-Bromo-5-(trifluoromethyl)benzonitrile features a trifluoromethyl group that imparts strong electron-withdrawing character and enhanced metabolic stability, while the bromine serves as a reactive handle for cross-coupling transformations. This aromatic nitrile integrates readily into complex molecular architectures under standard conditions.
2-Bromo-5-(trifluoromethyl)benzonitrile serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity profile. The bromo group facilitates efficient Suzuki, Stille, and Negishi couplings, while the trifluoromethyl and nitrile functionalities provide orthogonal handles for further functionalization. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing complex heterocyclic scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: