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Structure of 14844-73-6
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2,3-Dimethyl-1H-indole-5-carboxylic acid features a sterically hindered indole core with methyl groups at the 2- and 3-positions, enhancing stability and modulating electronic properties. The carboxylic acid at the 5-position enables direct coupling in peptide synthesis or conjugation workflows. This scaffold integrates readily into bioactive molecules requiring aromatic heterocyclic motifs with controlled polarity and solubility under standard bench conditions.
2,3-Dimethyl-1H-indole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of indole-based scaffolds with defined substitution patterns. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the methyl groups enhance metabolic stability and modulate lipophilicity. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for iterative synthetic workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P233-P235-P260-P261-P264-P270-P271-P280-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: