Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Hydroxymethyl)-1-methylindole

  • CAS No. 1485-22-9

  • Cat. No. CS-0021458
  • Purity≥97%
  • MDL No.MFCD04114774

*For research and further manufacturing use only, not for direct human use.

2-(Hydroxymethyl)-1-methylindole|CS-0021458

Structure of 1485-22-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1485-22-9
  • Cat. No. CS-0021458
  • Purity ≥97%
  • MDL No. MFCD04114774
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO
  • Molecular Weight 161.20
  • Synonym(s) (1-Methyl-1H-indol-2-yl)methanol; 1-Methyl-2-(hydroxymethyl)indole; 1-Methylindole-2-methanol; (1-METHYL-1H-INDOL-2-YL)-METHANOL
  • SMILES OCC(N1C)=CC2=C1C=CC=C2

Description

2-(Hydroxymethyl)-1-methylindole features a benzene-fused pyrrole core with a methyl group at the indole nitrogen and a hydroxymethyl substituent at the 2-position. This functionalized indole integrates readily into synthetic routes requiring polar, electron-rich heterocyclic scaffolds. The pendant hydroxyl enables further derivatization via oxidation or coupling reactions.

Application

2-(Hydroxymethyl)-1-methylindole serves as a versatile building block in medicinal chemistry, enabling straightforward functionalization at the indole C2 position. Its hydroxymethyl group facilitates oxidation to aldehyde or carboxylic acid derivatives, while the 1-methylindole core provides robust aromaticity and metabolic stability. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, supporting efficient access to complex heterocyclic scaffolds.

Synthesis

  • Route1

    References

    • Agnusdei, Marianna; Bandini, Marco; Melloni, Alfonso; Umani-Ronchi, Achille Journal of Organic Chemistry, 2003 , vol. 68, # 18 p. 7126 - 7129
  • Route2

    References

    • Chen, Wenyong; Sana, Kasinath; Jiang, Yi; Meyer, Esmerelda V. S.; Lapp, Stacey; Galinski, Mary R.; Liebeskind, Lanny S. Organometallics, 2013 , vol. 32, # 24 p. 7594 - 7611
  • Route3
    • null|null
      27421-51-8
    • ~%
    • In-stock
      2-(Hydroxymethyl)-1-methylindole|CS-0021458
      1485-22-9

    References

    • Lian, Yajing Lian; Davies, Huw M. L. Organic Letters, 2010 , vol. 12, # 5 p. 924 - 927

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   25.16
  • LogP   1.6706
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(Hydroxymethyl)-1-methylindole sigma2-(Hydroxymethyl)-1-methylindole manufacturer2-(Hydroxymethyl)-1-methylindole price2-(Hydroxymethyl)-1-methylindole structure2-(Hydroxymethyl)-1-methylindole SDSbuy 2-(Hydroxymethyl)-1-methylindole2-(Hydroxymethyl)-1-methylindole supplier2-(Hydroxymethyl)-1-methylindole uses2-(Hydroxymethyl)-1-methylindole molecular weightprice of 2-(Hydroxymethyl)-1-methylindole2-(Hydroxymethyl)-1-methylindole chemical name formula of 2-(Hydroxymethyl)-1-methylindole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label