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Structure of 14963-96-3
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4-Methoxyisobenzofuran-1,3-dione features a sterically hindered, electron-deficient dione core flanked by a methoxy group, enabling efficient coupling in transition-metal-catalyzed reactions. This bench-stable heterocycle integrates readily into complex molecular architectures under standard conditions.
4-Methoxyisobenzofuran-1,3-dione serves as a versatile synthon in medicinal chemistry, enabling efficient construction of biologically relevant heterocyclic scaffolds. Its ortho-quinone methide-like reactivity facilitates [4+2] cycloadditions and nucleophilic ring-opening reactions under mild conditions. The methoxy group enhances solubility and modulates electrophilicity, improving functional group tolerance during downstream transformations. This compound demonstrates excellent bench stability and ease of purification, making it well-suited for high-throughput synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: