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Structure of 149814-40-4
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This pyrrolidine derivative features a tert-butoxycarbonyl-protected amine and a silyl ether-stabilized hydroxyl group, enabling orthogonal handling in complex peptide synthesis. The stereochemistry at C2 and C4 ensures high diastereoselectivity during coupling steps.
(2S,4R)-1-(tert-Butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-2-carboxylic acid serves as a versatile chiral building block for the synthesis of pyrrolidine-containing bioactive molecules. The protected amine and silylated hydroxyl groups provide orthogonal functionality, enabling selective transformations in multi-step sequences. Bench-stable and compatible with standard coupling conditions, it facilitates efficient access to complex heterocyclic scaffolds used in medicinal chemistry and peptide analog development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: