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Structure of 151230-42-1
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6-Bromo-2-methylbenzoxazole is a halogenated heterocyclic scaffold featuring a bromine atom at the 6-position and a methyl group at the 2-position. This electron-deficient benzoxazole derivative exhibits enhanced reactivity in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard conditions. The steric profile of the methyl substituent improves regioselectivity, while the bromine moiety serves as a reliable coupling handle. This compound functions effectively as a building block in medicinal chemistry and materials science applications.
6-Bromo-2-methylbenzoxazole serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the methyl group enhances lipophilicity and metabolic stability. The benzoxazole core provides rigidity and improved binding affinity in target-directed synthesis. This compound exhibits excellent bench stability, ease of purification, and compatibility with standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: