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CS-W001157 4
Total: USD 88.00

(R)-1-methyl-4-(methylsulfinyl)benzene

  • CAS No. 1519-39-7

  • Cat. No. CS-M1249
  • Purity≥98%
  • MDL No.MFCD00151502

*For research and further manufacturing use only, not for direct human use.

(R)-1-methyl-4-(methylsulfinyl)benzene|CS-M1249

Structure of 1519-39-7

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General Information

  • CAS No. 1519-39-7
  • Cat. No. CS-M1249
  • Purity ≥98%
  • MDL No. MFCD00151502
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀OS
  • Molecular Weight 154.23
  • Synonym(s) (R)-(+)-Methyl p-tolyl sulfoxide
  • SMILES O=[S@](C)C(C=C1)=CC=C1C

Description

(R)-1-methyl-4-(methylsulfinyl)benzene features a chiral center at the methyl-substituted benzylic position, delivering enantioselective utility in asymmetric synthesis. The methylsulfinyl group provides a polar, oxygen-rich handle for stereoselective transformations, while the aromatic core ensures stability and compatibility with standard reaction conditions. This compound serves as a valuable scaffold in medicinal chemistry and catalyst design.

Synthesis

  • Route1
    • null|null
      917-64-6
    • In-stock
      (S)-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl) 4-methylbenzenesulfinate|CS-M1307
      1517-82-4
    • ~75%
    • In-stock
      (R)-1-methyl-4-(methylsulfinyl)benzene|CS-M1249
      1519-39-7

    References

    • Bode, Moira L.; Gates, Paul J.; Gebretnsae, Samson Y.; Vleggaar, Robert Tetrahedron, 2010 , vol. 66, # 11 p. 2026 - 2036
  • Route2

    References

    • Journal of the Chemical Society, Chemical Communications, , # 6 p. 639 - 640
  • Route3
    • null|null
      59153-43-4
    • ~95%
    • In-stock
      (R)-1-methyl-4-(methylsulfinyl)benzene|CS-M1249
      1519-39-7

    References

    • Shibata, Norio; Matsunaga, Mitsuharu; Nakagawa, Masaya; Fukuzumi, Takeo; Nakamura, Shuichi; Toru, Takeshi Journal of the American Chemical Society, 2005 , vol. 127, # 5 p. 1374 - 1375

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.73242
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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