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Structure of 1521806-48-3
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This pyrrole-based carboxylic acid features a methylsulfonyl group at the 1-position, enhancing solubility and metabolic stability. The electron-withdrawing sulfonyl moiety modulates acidity and reactivity, enabling integration into bioactive scaffolds. Ideal for medicinal chemistry campaigns requiring polar, bench-stable heterocyclic building blocks.
1-(Methylsulfonyl)-1H-pyrrole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient incorporation of a polar, metabolically stable sulfone group adjacent to a pyrrole core. Its carboxylic acid functionality facilitates direct amidation, esterification, or coupling reactions, while the methylsulfonyl group enhances solubility and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: