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Structure of 152300-60-2
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Ethyl 4-bromothiazole-5-carboxylate features a brominated thiazole core that enables direct functionalization in cross-coupling reactions. The ester group provides solubility in common organic solvents and serves as a handle for downstream derivatization. This bench-stable reagent integrates readily into synthetic sequences requiring heterocyclic building blocks with orthogonal reactivity.
Ethyl 4-bromothiazole-5-carboxylate serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-established bromo-substitution at the 4-position. The ester group offers compatibility with standard hydrolysis and derivatization protocols, while the thiazole core provides robust stability and favorable electronic properties for further functionalization. Its bench-stable nature and predictable reactivity make it ideal for modular scaffold construction in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H317-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: