Lot numbers can be found on the outside label of a product:
4-Chloroisoquinoline
-
CAS No. 1532-91-8
- Cat. No. CS-W019128
- Purity≥96%
- MDL No.MFCD00234490
*For research and further manufacturing use only, not for direct human use.
Structure of 1532-91-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 1532-91-8
- Cat. No. CS-W019128
- Purity ≥96%
- MDL No. MFCD00234490
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₆ClN
- Molecular Weight 163.60
- Synonym(s) 4-Chlorisochinolin
- SMILES ClC1=CN=CC2=CC=CC=C12
Description
4-Chloroisoquinoline is a bench-stable heterocyclic scaffold featuring a chlorine substituent at the 4-position, enhancing electrophilicity for directed functionalization. This electron-deficient core integrates readily into pharmaceutical intermediates and materials chemistry, enabling efficient coupling reactions under standard conditions.
Application
4-Chloroisoquinoline serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. Its electrophilic chlorine atom facilitates efficient functionalization at the C4 position while maintaining stability under standard reaction conditions. The scaffold is compatible with diverse protecting groups and supports modular assembly of complex isoquinoline-based architectures relevant to pharmaceutical development.
Synthesis
-
Route1
-
In-stock
23687-25-4 - ~%
-
In-stock
1532-91-8
References
-
US2005/20623 A1, ; Page 104 ;
-
-
Route2
-
In-stock
3336-49-0 - ~%
-
In-stock
1532-91-8
References
-
Journal of the American Chemical Society, , vol. 80, p. 3443,3448
-
-
Route3
-
108231-23-8 - ~86%
-
In-stock
1532-91-8
References
-
Urbanski, Jerzy; Wrobel, Leszek Bulletin of the Polish Academy of Sciences, Chemistry, 1988 , vol. 36, # 9-12 p. 417 - 424
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H319
|
|
|
Precautionary Statements : P305+P351+P338
|
|
Quality Control
Computational Chemistry Data
- TPSA 12.89
- LogP 2.8882
- H_Acceptors 1
- H_Donors 0
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 4-Chloroisoquinoline sigma4-Chloroisoquinoline manufacturer4-Chloroisoquinoline price4-Chloroisoquinoline structure4-Chloroisoquinoline SDSbuy 4-Chloroisoquinoline4-Chloroisoquinoline supplier4-Chloroisoquinoline uses4-Chloroisoquinoline molecular weightprice of 4-Chloroisoquinoline4-Chloroisoquinoline chemical name formula of 4-Chloroisoquinoline