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CS-W001157 4
Total: USD 88.00

4,4'-Bipiperidine

  • CAS No. 15336-72-8

  • Cat. No. CS-0155215
  • Purity≥97%
  • MDL No.MFCD01104315
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,4'-Bipiperidine|CS-0155215

Structure of 15336-72-8

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Description

4,4'-Bipiperidine is a rigid, electron-rich dipyridyl scaffold featuring two piperidine rings linked at their 4-positions. This structural motif provides enhanced conformational stability and improved solubility in polar solvents compared to related heterocycles. The molecule integrates readily into pharmaceutical intermediates, where its basic nitrogen atoms facilitate salt formation and modulate pharmacokinetic properties. Its well-defined steric profile supports selective binding in target-directed synthesis.

Application

4,4'-Bipiperidine serves as a versatile bis-heterocyclic scaffold in medicinal chemistry, enabling the construction of rigid, multi-donor systems for target engagement. Its robust bench stability and orthogonal reactivity support efficient functionalization at both nitrogen centers, facilitating downstream derivatization in ligand design. The molecule functions effectively as a core building block in the synthesis of bioactive compounds, particularly those requiring extended pharmacophores with controlled conformational flexibility.

General Information

  • CAS No. 15336-72-8
  • Cat. No. CS-0155215
  • Purity ≥97%
  • MDL No. MFCD01104315
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂
  • Molecular Weight 168.28
  • Synonym(s) [4,4']Bipiperidinyl
  • SMILES C1CNCCC1C2CCNCC2

Computational Chemistry Data

  • TPSA   24.06
  • LogP   0.9856
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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