1-Methyl-1H-pyrrolo[3,2-b]pyridine

Name: 1-Methyl-1H-pyrrolo[3,2-b]pyridine
Brand: ChemScene
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CAS No. 153374-33-5
Cat. No. CS-0161799
Purity≥98%
MDL No.MFCD12923567

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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1-Methyl-1H-pyrrolo[3,2-b]pyridine|CS-0161799

Structure of 153374-33-5

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Description

1-Methyl-1H-pyrrolo[3,2-b]pyridine is a heteroaromatic scaffold featuring a fused pyrrole-pyridine core with a methyl group at the nitrogen atom. This electron-rich system serves as a key building block in medicinal chemistry, offering enhanced solubility and metabolic stability. The compound integrates readily into molecular architectures requiring planar, polarizable frameworks for target engagement.

Application

1-Methyl-1H-pyrrolo[3,2-b]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically relevant scaffolds. Its well-defined reactivity profile supports direct functionalization at multiple sites, facilitates coupling reactions under standard conditions, and exhibits favorable bench stability for routine synthetic workflows.

General Information

CAS No. 153374-33-5
Cat. No. CS-0161799
Purity ≥98%
MDL No. MFCD12923567
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈N₂
Molecular Weight 132.16
Synonym(s) 1H-Pyrrolo[3,2-b]pyridine,1-methyl-(9CI)
SMILES CN1C=CC2=NC=CC=C21

Computational Chemistry Data

TPSA 17.82
LogP 1.5733
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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1-Methyl-1H-pyrrolo[3,2-b]pyridine

CAS No. 153374-33-5

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