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Structure of 154237-70-4
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4-Bromo-3-cyanopyridine features a pyridine core functionalized with bromo and cyano groups at adjacent positions, enabling direct coupling in cross-coupling reactions. The electron-deficient ring facilitates nucleophilic substitution, while the cyano moiety serves as a handle for downstream transformations. This compound offers high stability under standard conditions and is compatible with transition-metal catalysis.
4-Bromo-3-cyanopyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined reactivity profile. The cyano group provides a handle for nucleophilic transformations, while the bromo substituent facilitates efficient C–C bond formation under standard Suzuki, Stille, or Negishi conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds and API intermediates in scalable synthesis.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: