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Structure of 154698-93-8
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This silyl ether derivative features a tert-butyldiphenylsilyl-protected hydroxyl group paired with a labile oxazolidinone leaving group. It enables selective protection of alcohols in complex molecule synthesis, offering high stability under standard conditions and efficient deprotection via fluoride-mediated cleavage.
2-((tert-Butyldiphenylsilyl)oxy)-N-methoxy-N-methylacetamide serves as a robust silyl protecting group for alcohols, enabling selective protection under mild conditions. Its stability toward a broad range of reaction conditions and compatibility with diverse functional groups makes it ideal for complex molecule synthesis. The tert-butyldiphenylsilyl moiety facilitates easy removal via fluoride-mediated cleavage, while the N-methoxy-N-methylcarbamate group ensures efficient activation in coupling reactions. This reagent is particularly valuable in carbohydrate and natural product synthesis workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: