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Structure of 155265-57-9
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2-Bromo-6-methylpyridine-3-carbonitrile features a strategically positioned bromine atom and electron-withdrawing nitrile group on a methyl-substituted pyridine scaffold, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The sterically accessible C2 position facilitates efficient derivatization under standard conditions, while the bench-stable, moisture-tolerant nature ensures reliable handling in synthetic workflows.
2-Bromo-6-methylpyridine-3-carbonitrile serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromo and cyano functional groups. The methyl substituent enhances electron density at the pyridine ring, improving reactivity in C–H functionalization and Suzuki-Miyaura coupling protocols. Bench-stable and compatible with standard purification methods, it facilitates efficient construction of complex pyridine-based scaffolds used in pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: