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Structure of 156001-49-9
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4-Bromo-1-(bromomethyl)-2-methylbenzene features a bromomethyl group flanked by electron-withdrawing bromine and methyl substituents, enabling selective functionalization in late-stage diversification. This ortho-disubstituted aryl halide exhibits enhanced reactivity in cross-coupling processes due to steric and electronic modulation.
4-Bromo-1-(bromomethyl)-2-methylbenzene serves as a versatile dihalogenated building block for palladium-catalyzed cross-coupling reactions. The bromomethyl group enables direct functionalization via nucleophilic substitution, while the aryl bromide supports Suzuki, Stille, and Negishi couplings. Bench-stable and compatible with standard purification methods, it facilitates efficient construction of complex biaryl and heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302+H312+H332-H314
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: