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Structure of 156682-52-9
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1,4-Dibromo-2,3-difluorobenzene features a rigid aromatic core with complementary halogen substituents enabling precise cross-coupling reactions. The bromine atoms serve as effective coupling handles, while the fluorine groups enhance electronic modulation and metabolic stability in synthetic intermediates.
1,4-Dibromo-2,3-difluorobenzene serves as a versatile building block in cross-coupling reactions, enabling the construction of complex fluorinated aromatic scaffolds. Its orthogonal halogen reactivity facilitates sequential Pd-catalyzed couplings, while the difluoro substitution enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and is amenable to standard purification protocols, making it well-suited for iterative synthetic strategies in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364
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Lot numbers can be found on the outside label of a product: