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Structure of 15733-87-6
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2-Bromoquinoline-4-carboxylic acid features a brominated quinoline scaffold with a carboxylic acid group at the 4-position, enabling direct functionalization in cross-coupling and bioconjugation workflows. The electron-deficient heterocycle pairs effectively with palladium catalysts, while the acidic proton facilitates salt formation and purification under standard conditions. This compound serves as a key intermediate for pharmaceutical and agrochemical lead discovery.
2-Bromoquinoline-4-carboxylic acid serves as a versatile building block for the synthesis of quinoline-based pharmaceuticals and functional materials. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates derivatization via amide, ester, or acyl chloride formation. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: