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Structure of 157599-02-5
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DOTA-amide delivers a robust, macrocyclic chelating scaffold with high affinity for lanthanide and transition metal ions. This stable complexation platform enables precise radiolabeling in diagnostic imaging and targeted therapeutics, leveraging the amide functionality for enhanced solubility and metabolic resistance under physiological conditions.
DOTA-amide serves as a robust macrocyclic chelator for radiometal coordination, enabling stable conjugation of isotopes such as ⁶⁸Ga, ⁶⁴Cu, and ¹⁵³Gd in bioconjugate applications. Its amide terminus facilitates site-specific coupling to peptides or proteins via standard amidation protocols, offering excellent stability, high functional group tolerance, and straightforward purification—making it ideal for developing PET/SPECT imaging agents and targeted radiotherapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: