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Structure of 15760-35-7
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3-Methylenecyclobutanecarbonitrile features a strained cyclobutane ring fused to an exocyclic methylene group and a nitrile handle, enabling direct incorporation into cycloaddition cascades. The electron-deficient alkene facilitates rapid Diels-Alder reactions, while the nitrile moiety offers downstream functionalization potential. This reactive scaffold streamlines access to complex nitrogen-containing carbocycles under mild conditions.
3-Methylenecyclobutanecarbonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized cyclobutane scaffolds. Its exocyclic methylene group facilitates conjugate additions and Diels-Alder reactions, while the nitrile moiety offers a robust handle for downstream transformations including hydrolysis, reduction, or nucleophilic addition. The compound exhibits good bench stability and compatibility with diverse reaction conditions, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS02,GHS06
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Signal Word : Danger
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UN#: 1992
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Class : 3 (6.1)
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Packing Group : Ⅲ
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Hazard Statements : H226-H301-H312+H332-H315-H317-H319-H335
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P272-P280-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: