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Structure of 15789-03-4
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3-Hydroxy-N,N-dimethylbenzamide features a phenolic hydroxyl group flanked by an electron-rich aromatic ring and a sterically hindered dimethylamide moiety. This combination imparts enhanced solubility in polar organic solvents and stability under standard bench conditions, enabling direct incorporation into complex synthetic sequences without requiring protective group manipulation.
3-Hydroxy-N,N-dimethylbenzamide serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via standard amidation and coupling protocols. Its hydroxyl group provides a handle for derivatization, while the N,N-dimethylamide functionality ensures good metabolic stability and favorable solubility profiles. Bench-stable and readily purified by recrystallization or chromatography, it functions effectively in multi-step syntheses requiring orthogonal functional group handling.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: