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Structure of 157942-12-6
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Methyl 3-hydroxy-4-iodobenzoate features a strategically positioned hydroxyl group and iodine atom on the aromatic ring, enabling selective cross-coupling reactions. This bench-stable ester integrates readily into complex molecular architectures, particularly in pharmaceutical and agrochemical synthesis where halogen-directed functionalization is required.
Methyl 3-hydroxy-4-iodobenzoate serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to functionalized biaryls and heterocycles. The ortho-hydroxyl group provides a handle for directed metalation or protection, while the iodide facilitates reliable Suzuki, Stille, and Negishi couplings. Bench-stable and readily purified by column chromatography, it offers predictable reactivity in complex molecule assembly workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: