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Structure of 159217-89-7
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tert-Butyl (4-iodophenyl)carbamate delivers a robust, bench-stable platform for installing iodinated aryl handles in late-stage functionalization. The carbamate moiety enables efficient deprotection under mild acidic conditions, while the para-iodo group supports diverse cross-coupling reactions, including Suzuki-Miyaura and Sonogashira transformations. This reagent combines high stability with predictable reactivity, simplifying synthetic workflows in medicinal chemistry and materials development.
tert-Butyl (4-iodophenyl)carbamate serves as a stable, bench-ready precursor for the introduction of 4-iodophenylamine units in cross-coupling reactions. The carbamate group provides excellent protection of the amine functionality, enabling orthogonal reactivity in multi-step syntheses. Its iodide moiety facilitates reliable Suzuki, Stille, and Negishi couplings, offering high functional group tolerance and ease of purification. This compound functions as a key building block in the synthesis of biaryl scaffolds relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07,GHS09
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Signal Word : Warning
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H317-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: