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Structure of 15963-40-3
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Methyl 3-methylidenecyclobutane-1-carboxylate features a strained cyclobutane core with an exocyclic methylene group, enabling participation in cycloadditions and ring-expansion reactions. This electron-deficient alkene integrates readily into synthetic sequences requiring constrained, reactive intermediates under standard conditions.
Methyl 3-methylidenecyclobutane-1-carboxylate serves as a versatile cyclobutane-based building block for the synthesis of strained ring systems and bioactive scaffolds. Its exocyclic methylene group enables efficient Diels-Alder reactions, Michael additions, and metal-catalyzed cyclizations. The ester functionality offers facile manipulation via hydrolysis or reduction, while the molecule exhibits good bench stability and ease of purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: