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Structure of 159870-80-1
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5-Fluoro-2-iodopyridine serves as a key building block in cross-coupling chemistry, featuring a reactive iodide and electron-deficient pyridine ring. This combination enables efficient palladium-catalyzed transformations, including Suzuki-Miyaura and Buchwald-Hartwig reactions. The fluorine substituent enhances metabolic stability and modulates electronic properties in pharmaceutical intermediates.
5-Fluoro-2-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. The ortho-iodo group facilitates palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings, while the meta-fluoro substituent offers complementary reactivity for further functionalization. Its bench-stable nature and predictable regioselectivity make it ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: