Tetrahydrofuran-2-yl acetate

Name: Tetrahydrofuran-2-yl acetate
Brand: ChemScene
Availability: InStock
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CAS No. 1608-67-9
Cat. No. CS-0160246
Purity≥95%
MDL No.MFCD09907739

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

Tetrahydrofuran-2-yl acetate serves as a stable, moisture-tolerant acetyl donor in synthetic transformations. This bench-stable ester integrates readily into complex molecule assembly, offering selective protection and activation under mild conditions. Its cyclic ether backbone enhances solubility and compatibility across organic and biopharmaceutical workflows.

Application

Tetrahydrofuran-2-yl acetate serves as a stable, bench-friendly acetyl protecting group for alcohols and amines, enabling selective protection in complex molecule synthesis. It functions as a versatile building block in the construction of heterocyclic scaffolds and bioactive intermediates, offering excellent compatibility with standard coupling and reduction protocols. Its clean deprotection under mild acidic or basic conditions facilitates efficient synthetic workflows.

General Information

CAS No. 1608-67-9
Cat. No. CS-0160246
Purity ≥95%
MDL No. MFCD09907739
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₀O₃
Molecular Weight 130.14
Synonym(s) Tetrahydro-2-furyl acetate
SMILES CC(OC1OCCC1)=O

Computational Chemistry Data

TPSA 35.53
LogP 0.686
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Key Words

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Tetrahydrofuran-2-yl acetate

CAS No. 1608-67-9

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